BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide composed of 15 amino acids. It is derived from a partial sequence of a protective protein found in human gastric juice and has been the subject of extensive in vitro and animal model research across multiple biological systems.
Compound Specifications
- Molecular Formula: C₆₂H₉₈N₁₆O₂₂
- Molecular Weight: 1,419.5 g/mol
- Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
- CAS Number: 137525-51-0
- Purity: ≥98% (HPLC verified)
- Form: Lyophilized powder
- Vial Contents: 5mg
- Appearance: White to off-white powder
- Solubility: Soluble in water and acetic acid
Research Background
BPC-157 has been investigated in preclinical research settings for its role in gastrointestinal mucosal integrity, angiogenesis modulation, and connective tissue response. Published research has examined its interaction with growth hormone receptor expression, nitric oxide synthesis pathways, and cytokine signaling in various tissue models.
It is classified as a stable gastric pentadecapeptide, meaning it maintains structural integrity in human gastric juice — a property that has made it a subject of interest in gastrointestinal research. Studies have also explored its behavior in musculoskeletal tissue models, tendon fibroblast cultures, and neurological research contexts.
Research Classification
- Primary: Tissue & Regenerative Peptides
- Secondary: Gastrointestinal Research
- Research areas: Angiogenesis, mucosal protection, connective tissue biology, nitric oxide modulation
Storage and Handling
- Store lyophilized peptide at -20°C, away from light and moisture
- Upon reconstitution, store at 4°C and use within 30 days
- Avoid repeated freeze-thaw cycles — aliquot before freezing if multiple uses are anticipated
- Handle using appropriate PPE in a controlled laboratory environment
- Reconstitution solvent: bacteriostatic water or sterile acetic acid (0.1%)
Batch and Quality Information
- Testing: Every batch independently verified by a third-party laboratory
- Analysis: HPLC purity testing and mass spectrometry identity confirmation
- COA: Certificate of Analysis available on request — email support@hardrocklabs.com with product name and order number
Selected Research References
- Sikiric P, et al. “Stable gastric pentadecapeptide BPC 157.” Current Pharmaceutical Design. 2018.
- Chang CH, et al. “The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration.” Journal of Applied Physiology. 2011.
- Tevzadze L, et al. “BPC 157 and central nervous system.” Biomedicines. 2023.
For Research Use Only
This product is intended exclusively for in vitro laboratory research and scientific study by qualified research professionals. It is not approved by the U.S. Food and Drug Administration for human or veterinary use, and is not intended for diagnostic, therapeutic, or any other clinical application. Must be handled in accordance with applicable laboratory safety regulations.
